Publications

Functional specialisation and coordination of myonuclei. Korb A, Tajbakhsh S*, Comai G*. Biological Reviews. 2024 Mar 13. doi: 10.1111/brv.13063 (*co-corresponding)

Interplay between Pitx2 and Pax7 temporally governs specification of extraocular muscle progenitors. Mao Kuriki, Glenda Comai*, Shahragim Tajbakhsh*. bioRxiv. doi: https://doi.org/10.1101/2023.08.24.554745. (*co-corresponding)

Extraocular muscle stem cells exhibit distinct cellular properties associated with non-muscle molecular signatures. Di Girolamo D, Benavente-Diaz M, Murolo M, Grimaldi A, Thomas Lopes P, Evano B, Kuriki M, Gioftsidi S, Laville V, Tinevez J-Y, Letort G, Mella S, Tajbakhsh S*, Comai G*.  Development . 2024 Feb 15;151(4):dev202144. doi: 10.1242/dev.202144(*co-corresponding)

Overlapping functions of SIX homeoproteins during embryonic myogenesis. Wurmser M, Madani R, Chaverot N, Backer S, Borok M, Dos Santos M, Comai G, Tajbakhsh S, Relaix F, Santolini M, Sambasivan R, Jiang R, Maire P. PLoS Genet . 2023 Jun 2;19(6):e1010781. doi: 10.1371/journal.pgen.1010781. PMID: 37267426

A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation. Vallecillo-García P, Orgeur M, Comai G, Poehle-Kronawitter S, Fischer C, Gloger M, Dumas C, Giesecke-Thiel C, Sauer S, Tajbakhsh S, Höpken U, Stricker S. Immunity . 2023 Jun 13;56(6):1204-1219.e8. doi: 10.1016/j.immuni.2023.04.014. PMID: 37160119

Identification of bipotent progenitors that give rise to myogenic and connective tissues in mouse. Grimaldi A, Comai G, Mella Sebastien, Tajbakhsh S. eLife 2022 Feb 28:11:e70235. doi: 10.7554/eLife.70235. PMID: 35225230

Unexpected contribution of fibroblasts to muscle lineage as a mechanism for limb muscle patterning. Esteves de Lima J, Blavet C, Bonnin MA, Hirsinger E, Comai G, Yvernogeau L, Delfini MC, Bellenger L, Mella S, Nassari S, Robin C, Schweitzer R, Fournier-Thibault C, Jaffredo T, Tajbakhsh S, Relaix F, Duprez D. Nat Commun. 2021 Jun 22;12(1):3851. doi: 10.1038/s41467-021-24157-x. PMID: 34158501.

Dynamics of myogenic differentiation using a novel Myogenin knock-in reporter mouse. Benavente-Diaz M, Comai G, Di Girolamo D, Langa F, Tajbakhsh S. Skeletal Muscle. 2021 Feb 18;11(1):5. doi: 10.1186/s13395-021-00260-x. PMID: 33602287. 

Local retinoic acid signaling directs emergence of the extraocular muscle functional unit. Comai GE*, Tesařová M, Dupé V, Rhinn M, Vallecillo-García P, da Silva F, Feret B, Exelby K, Dollé P, Carlsson L, Pryce B, Spitz F, Stricker S, Zikmund T, Kaiser J, Briscoe J, Schedl A, Ghyselinck NB, Schweitzer R, Tajbakhsh S*. PLoS Biol. 2020 Nov 17;18(11):e3000902. doi: 10.1371/journal.pbio.3000902. eCollection 2020 Nov. PMID: 33201874. (* co-corresponding authors)

Transcriptome and epigenome diversity and plasticity of muscle stem cells following transplantation. Evano B, Gill D, Hernando-Herraez I, Comai G, Stubbs TM, Commere PH, Reik W, Tajbakhsh S. PLoS Genet. 2020 Oct 30;16(10):e1009022. doi: 10.1371/journal.pgen.1009022. eCollection 2020 Oct. PMID: 33125370.

Dullard-mediated Smad1/5/8 inhibition controls mouse cardiac neural crest cells condensation and outflow tract septation. Darrigrand JF, Valente M, Comai G, Martinez P, Petit M, Nishinakamura R, Osorio DS, Renault G, Marchiol C, Ribes V, Cadot B. eLife. 2020 Feb 27;9:e50325. doi: 10.7554/eLife.50325. PMID: 32105214.

An interactive and intuitive visualisation method for X-ray computed tomography data of biological samples in 3D Portable Document Format. Tesařová M, Heude E, Comai G, Zikmund T, Kaucká M, Adameyko I, Tajbakhsh S, Kaiser J. Scientific Reports. 2019 Oct 17;9(1):14896. doi: 10.1038/s41598-019-51180-2. PMID: 31624273.

Muscle-selective RUNX3 dependence of sensorimotor circuit development. Wang Y, Wu H, Zelenin P, Fontanet P, Wanderoy S, Petitpré C, Comai G, Bellardita C, Xue-Franzén Y, Huettl RE, Huber AB, Tajbakhsh S, Kiehn O, Ernfors P, Deliagina TG, Lallemend F, Hadjab S. Development. 2019 Oct 24;146(20):dev181750. doi: 10.1242/dev.181750. PMID: 31575648.

A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle. Comai G*, Heude E*, Mella S, Paisant S, Pala F, Gallardo M, Langa F, Kardon G, Gopalakrishnan S, Tajbakhsh S. eLife 2019 Sep 19;8:e47460. doi: 10.7554/eLife.47460. PMID: 31535973. (* co-first authors)

A cell fitness selection model for neuronal survival during development. Wang Y, Wu H, Fontanet P, Codeluppi S, Akkuratova N, Petitpré C, Xue-Franzén Y, Niederreither K, Sharma A, Da Silva F, Comai G, Agirman G, Palumberi D, Linnarsson S, Adameyko I, Moqrich A, Schedl A, La Manno G, Hadjab S, Lallemend F. Nat Commun. 2019 Sep 12;10(1):4137. doi: 10.1038/s41467-019-12119-3. PMID: 31515492.

Genetic and Molecular Insights Into Genotype-Phenotype Relationships in Osteopathia Striata With Cranial Sclerosis (OSCS) Through the Analysis of Novel Mouse Wtx Mutant Alleles. Comai G, Boutet A, Tanneberger K, Massa F, Rocha AS, Charlet A, Panzolini C, Jian Motamedi F, Brommage R, Hans W, Funck-Brentano T, Hrabe de Angelis M, Hartmann C, Cohen-Solal M, Behrens J, Schedl A. J Bone Miner Res. 2018 May;33(5):875-887. doi: 10.1002/jbmr.3387. Epub 2018 Mar 1. PMID: 29329488.

A knock-in mouse line conditionally expressing the tumor suppressor WTX/AMER1. Boutet A, Comai G, Charlet A, Jian Motamedi F, Dhib H, Bandiera R, Schedl A. Genesis. 2017 Nov;55(11). doi: 10.1002/dvg.23074. Epub 2017 Oct 16. PMID: 28960679.

A Cranial Mesoderm Origin for Esophagus Striated Muscles. Gopalakrishnan S, Comai G, Sambasivan R, Francou A, Kelly RG, Tajbakhsh S. Developmental Cell. 2015 Sep 28;34(6):694-704. doi: 10.1016/j.devcel.2015.07.003. Epub 2015 Sep 17. PMID: 26387456.

Variations in the efficiency of lineage marking and ablation confound distinctions between myogenic cell populations. Comai G*, Sambasivan R*, Gopalakrishnan S, Tajbakhsh S. Developmental Cell. 2014 Dec 8;31(5):654-67. doi: 10.1016/j.devcel.2014.11.005. PMID: 25490270. (* co-first authors)

Molecular and cellular regulation of skeletal myogenesis. Comai G, Tajbakhsh S. Curr Top Dev Biol. 2014;110:1-73. doi: 10.1016/B978-0-12-405943-6.00001-4. PMID: 25248473 Review.

Embryonic founders of adult muscle stem cells are primed by the determination gene Mrf4. Sambasivan R, Comai G, Le Roux I, Gomès D, Konge J, Dumas G, Cimper C, Tajbakhsh S. Dev Biol. 2013 Sep 1;381(1):241-55. doi: 10.1016/j.ydbio.2013.04.018. Epub 2013 Apr 25. PMID: 23623977.

The WTX/AMER1 gene family: evolution, signature and function. Boutet A, Comai G, Schedl A. BMC Evol Biol. 2010 Sep 15;10:280. doi: 10.1186/1471-2148-10-280. PMID: 20843316. 

Expression patterns of the Wtx/Amer gene family during mouse embryonic development. Comai G, Boutet A, Neirijnck Y, Schedl A. Dev Dyn. 2010 Jun;239(6):1867-78. doi: 10.1002/dvdy.22313.PMID: 20503382.

Glutathione produced by Rhizobium tropici is important to prevent early senescence in common bean nodules. Muglia C, Comai G, Spegazzini E, Riccillo PM, Aguilar OM. FEMS Microbiol Lett. 2008 Sep;286(2):191-8. doi: 10.1111/j.1574-6968.2008.01285.x. Epub 2008 Jul 23. PMID: 18657108.